CJC1295-Ipamorelin Blend

What Is CJC-1295?

CJC-1295 with DAC is a modified GHRH analogue consisting of amino acid substitutions that improve stability and resistance to enzymatic degradation. The attached Drug Affinity Complex enables prolonged circulation by binding to serum albumin, allowing sustained stimulation of growth hormone secretion over several days.

Unlike direct growth hormone administration, CJC-1295 with DAC is designed to stimulate the body’s natural pulsatile release of growth hormone through activation of GHRH receptors.

Mechanism of Action

CJC-1295 with DAC acts as an agonist of the Growth Hormone-Releasing Hormone (GHRH) receptor located on pituitary somatotroph cells.

Activation of these receptors results in:

• Stimulation of endogenous growth hormone (GH) release.
• Increased circulating insulin-like growth factor-1 (IGF-1) through hepatic GH signaling.
• Preservation of physiological GH pulsatility rather than continuous hormone exposure.
• Extended biological activity through reversible albumin binding provided by the DAC modification.

The prolonged half-life distinguishes CJC-1295 with DAC from shorter-acting GHRH analogues.

Summary of Publicly Available Research

Preclinical and early clinical studies have demonstrated that CJC-1295 with DAC can produce sustained elevations in circulating GH and IGF-1 following a single administration. Research has reported prolonged pharmacodynamic activity lasting several days due to albumin binding.

Publicly available studies have investigated its effects on:

• Growth hormone secretion
• IGF-1 regulation
• Endocrine physiology
• Protein metabolism
• Body composition
• Healthy aging models
• Recovery following physiological stress

While results have been encouraging in research settings, additional large-scale clinical investigations are necessary to fully characterize long-term safety and efficacy.

Key Research Areas

Current and historical research includes:

• Growth hormone physiology
• Endocrine regulation
• IGF-1 signaling
• Healthy aging research
• Lean body mass and body composition
• Muscle protein synthesis
• Tissue repair mechanisms
• Bone metabolism
• Sleep physiology
• Exercise recovery
• Metabolic regulation

Chemical Information

Compound Name: CJC-1295 with DAC

Peptide Class: Growth Hormone-Releasing Hormone (GHRH) analogue

Modification: Drug Affinity Complex (DAC)

Molecular Formula: Variable depending on formulation

Molecular Weight: Approximately 4,700–4,800 Da

Appearance: White to off-white lyophilized powder

Solubility: Water-soluble following reconstitution

Typical Presentation: 10 mg sterile lyophilized peptide

Storage Recommendations

Before Reconstitution

• Store refrigerated at 2-8°C (36-46°F).
• Protect from moisture, excessive heat, and direct light.
• Keep vial sealed until use.

After Reconstitution (Research Settings)

• Store at 2-8°C.
• Avoid repeated freeze-thaw cycles.
• Use sterile laboratory technique during handling.
• Discard if discoloration or visible particulates develop.

COA (Certificate of Analysis)

Each production batch should include a Certificate of Analysis containing:

• Product Name
• Lot Number
• Batch Number
• Manufacturing Date
• Expiration Date
• Identity Confirmation
• Peptide Purity (typically determined by HPLC)
• Molecular Weight Verification (Mass Spectrometry)
• Appearance
• Fill Quantity Verification
• Sterility Testing (where applicable)
• Storage Recommendations
• Quality Control Release Authorization

Refer to the lot-specific COA supplied with the product for analytical results.

Customer Reviews

★★★★★ Excellent Research Quality

Consistently high-quality peptide with clear labeling and professional packaging.

★★★★★ Reliable Product

Arrived well packaged with supporting documentation and excellent presentation.

★★★★★ Laboratory Standard

Clean lyophilized appearance and dependable quality for research applications.

★★★★★ Highly Satisfied

Excellent consistency between batches and prompt shipping.

Frequently Asked Questions

What does DAC stand for?

DAC stands for Drug Affinity Complex, a modification that allows CJC-1295 to bind to serum albumin and remain active for a substantially longer period.

How is CJC-1295 with DAC different from Mod GRF (1-29)?

CJC-1295 with DAC has a significantly extended half-life due to albumin binding, whereas Mod GRF (1-29) is a shorter-acting GHRH analogue designed for transient receptor activation.

What is the primary focus of current research?

Research primarily investigates growth hormone regulation, IGF-1 signaling, metabolism, tissue repair, body composition, and endocrine physiology.

What does the lyophilized powder look like?

It typically appears as a white to off-white sterile powder or compact cake before reconstitution.

How should it be stored?

Store refrigerated at 2-8°C before and after reconstitution, protected from light and moisture, using appropriate sterile laboratory handling procedures.

Related Products

Researchers commonly pair CJC-1295 with DAC with:

• Ipamorelin
• GHRP-2
• GHRP-6
• Sermorelin
• Mod GRF (1-29)
• IGF-1 LR3
• PEG-MGF
• Bacteriostatic Water
• Sterile Syringes
• Alcohol Prep Pads

Disclaimer: This product is intended for laboratory research purposes only. It is not approved for human or veterinary use, and no therapeutic or diagnostic claims are made regarding its use.