What Is SS-31?

SS-31, also known as Elamipretide, is a synthetic tetrapeptide specifically designed to target the inner mitochondrial membrane. Unlike many peptides that act through cell surface receptors, SS-31 readily penetrates cells and accumulates within mitochondria, where it interacts with mitochondrial phospholipids involved in energy production.

Its unique mitochondrial targeting has made it a valuable research tool for studying diseases and conditions associated with mitochondrial dysfunction.

Mechanism of Action

Although research is ongoing, published studies suggest SS-31 may:

• Selectively target the inner mitochondrial membrane
• Bind to cardiolipin, a key mitochondrial phospholipid
• Improve mitochondrial electron transport efficiency
• Reduce production of reactive oxygen species (ROS)
• Help preserve ATP (cellular energy) production
• Protect mitochondrial structure and function during cellular stress
• Support cellular survival under oxidative conditions

These mechanisms remain subjects of active scientific investigation.

Summary of Publicly Available Research

Published preclinical and clinical research has explored SS-31 in several areas, including:

• Mitochondrial dysfunction
• Age-related cellular decline
• Heart failure and cardiovascular research
• Skeletal muscle performance
• Kidney injury models
• Neurodegenerative disease research
• Diabetes-related complications
• Ischemia-reperfusion injury
• Fatigue and exercise physiology
• Rare mitochondrial disorders

Research has demonstrated encouraging effects on mitochondrial function in experimental models. However, further clinical studies are required to fully establish long-term safety and therapeutic potential.

Key Research Areas

Researchers commonly investigate SS-31 in:

• Mitochondrial biology
• Cellular energy metabolism
• Oxidative stress
• Healthy aging
• Cardiovascular research
• Skeletal muscle physiology
• Neurodegeneration
• Kidney protection
• Metabolic disorders
• Regenerative medicine

Chemical Information

Storage Recommendations

For optimal stability:

• Store lyophilized peptide at 2–8°C for short-term storage.
• Store at -20°C or below for long-term preservation.
• Protect from moisture, heat, and direct sunlight.
• Avoid repeated freeze-thaw cycles after reconstitution.
• Store reconstituted solutions according to standard laboratory protocols.

Certificate of Analysis (COA)

Each production batch undergoes rigorous quality control testing before release.

A typical COA includes:

• Product identification
• Batch/Lot number
• HPLC purity analysis
• Mass spectrometry confirmation
• Appearance
• Net peptide content
• Manufacturing date
• Quality control approval

Batch-specific Certificates of Analysis are available upon request.

Customer Reviews

★★★★★ Outstanding Purity

“Excellent research-grade peptide with consistent quality and complete analytical documentation.”

★★★★★ Reliable Laboratory Material

“Our research team has been impressed with the purity, packaging, and batch consistency.”

★★★★★ Professional Service

“Secure packaging, fast shipping, and high-quality research material that meets laboratory expectations.”

Customer reviews reflect product quality and purchasing experience only and should not be interpreted as evidence of therapeutic effectiveness or research outcomes.

Frequently Asked Questions

Is SS-31 intended for human use?

No. SS-31 is supplied strictly for laboratory and scientific research purposes only.

What does each vial contain?

Each vial contains 10 mg of lyophilized SS-31 (Elamipretide) peptide.

Is a Certificate of Analysis available?

Yes. Every production batch includes or is supported by a batch-specific COA confirming purity and identity.

How should SS-31 be stored?

Store refrigerated at 2–8°C for short-term storage or frozen at -20°C for long-term preservation.

What research applications commonly involve SS-31?

Researchers study SS-31 in mitochondrial biology, oxidative stress, cardiovascular health, skeletal muscle physiology, neurodegeneration, aging, kidney protection, and metabolic disease research.

What is the purity of the product?

Purity is verified through analytical testing, with the exact value provided on the batch-specific Certificate of Analysis.

Related Products

Researchers investigating SS-31 frequently explore:

• MOTS-c
• Humanin
• BPC-157
• TB-500
• GHK-Cu
• KPV
• Epitalon
• CJC-1295 with DAC
• Ipamorelin
• Thymosin Alpha-1 (TA-1)

Research Use Only: This product is intended exclusively for laboratory research by qualified professionals. It is not approved for human consumption, medical treatment, veterinary use, or diagnostic purposes. All research should be conducted in accordance with applicable institutional and regulatory guidelines.