What Is KPV?

KPV is a three-amino-acid peptide consisting of Lysine, Proline, and Valine. It represents the C-terminal fragment of α-MSH while retaining many of the parent peptide’s anti-inflammatory effects without significant hormonal activity.

Researchers study KPV for its potential to regulate inflammatory responses and support epithelial barrier integrity in various experimental models.

Mechanism of Action

Although research is ongoing, studies suggest KPV may:

• Modulate inflammatory cytokine production
• Reduce activation of the NF-κB inflammatory signaling pathway
• Influence innate immune responses
• Help regulate macrophage activity
• Support epithelial barrier function
• Reduce oxidative stress associated with inflammation
• Promote tissue repair in experimental models

These mechanisms continue to be investigated and are not fully understood.

Summary of Publicly Available Research

Published research has explored KPV across multiple experimental settings, including:

• Inflammatory bowel disease (IBD) models
• Ulcerative colitis research
• Crohn’s disease models
• Skin inflammation studies
• Wound healing research
• Intestinal epithelial barrier function
• Autoimmune disease models
• General immune regulation

Preclinical studies have demonstrated encouraging anti-inflammatory activity, although additional clinical research is required to better understand its safety and potential applications.

Key Research Areas

KPV is commonly investigated in:

• Inflammation research
• Gastrointestinal health
• Immune system regulation
• Intestinal permeability
• Skin repair and regeneration
• Wound healing
• Autoimmune disease models
• Cytokine signaling
• Oxidative stress
• Tissue regeneration

Chemical Information

Storage Recommendations

To preserve peptide stability:

• Store lyophilized peptide at 2–8°C for short-term storage.
• For long-term storage, keep at -20°C or below.
• Protect from moisture, excessive heat, and direct sunlight.
• Avoid repeated freeze-thaw cycles after reconstitution.
• Store prepared solutions according to established laboratory protocols.

Certificate of Analysis (COA)

Each batch undergoes quality assurance testing prior to release.

Typical COA includes:

• Product identification
• Batch/Lot number
• HPLC purity analysis
• Mass spectrometry verification
• Appearance
• Net peptide content
• Manufacturing date
• Quality control approval

Batch-specific Certificates of Analysis are available upon request.

Customer Reviews

★★★★★ Excellent Purity

“High-quality peptide with consistent analytical documentation. Packaging and shipping exceeded expectations.”

★★★★★ Great Research Material

“Our laboratory has used this peptide across several inflammation studies with reliable batch consistency.”

★★★★★ Professional Quality

“Well-packaged product supported by comprehensive quality control documentation.”

Customer reviews relate to product quality and purchasing experience only and do not constitute claims regarding research outcomes or therapeutic effects.

Frequently Asked Questions

Is KPV intended for human use?

No. KPV is supplied strictly for laboratory and scientific research purposes only.

What does each vial contain?

Each vial contains 10 mg of lyophilized KPV peptide.

Is a Certificate of Analysis included?

Yes. A batch-specific COA is available to verify purity and identity.

How should KPV be stored?

Store refrigerated at 2–8°C or frozen at -20°C for extended storage.

What is KPV commonly researched for?

Researchers investigate KPV in studies involving inflammation, gastrointestinal disorders, immune regulation, wound healing, and tissue repair.

What is the purity of the product?

Purity is confirmed through analytical testing, with exact values provided on the batch-specific Certificate of Analysis.

Related Products

Researchers studying KPV often explore complementary research peptides, including:

• BPC-157
• TB-500 (Thymosin Beta-4)
• GHK-Cu
• LL-37
• Thymosin Alpha-1 (TA-1)
• Semax
• Selank
• Epitalon
• MOTS-c
• ARA-290

Research Use Only: This product is intended solely for laboratory research by qualified professionals. It is not approved for human consumption, medical treatment, veterinary use, or diagnostic purposes. All studies should be conducted in accordance with applicable institutional and regulatory guidelines.